Description
Pramipexole
Pramipexole, also known as Mirapex is a dopamine agonist. This drug is commonly supplementing bodybuilders during anabolic-androgenic steroid (AAS) cycles where 19-nor compounds (such as Tren and Deca). People use this compound in therapeutic settings to treat a number of different conditions and diseases.
Miragen, known as Mirapex (or Pramipexole) is a strong dopamine agonist drug used in modern medicine to treat Parkinson’s disease and restless legs syndrome. Its use becomes invaluable while running 19-nor compounds (Tren and Deca) It decreases elevated prolactin levels and the related side effects (such as erectile dysfunction, or “Deca Dick”). Additionally, while not a SERM or AI, it falls into this category of medication in mitigating the potential side effects that certain anabolic steroids can bring. The degree of the side effects from elevated prolactin levels will largely depend on genetics. Some users will be more genetically predisposed to certain side effects. For those sensitive to prolactin, this popular medication can aid by mitigating side effects. These include gynecomastia, erectile dysfunction.
Positive effects of Pramipexole
The positive effects of Pramipexole medically revolve primarily on relieving the symptoms of Parkinson’s disease and improving the mood of the patient. However, the drug is also used by some performance enhancing athletes, primarily to combat a specific kind of gynecomastia and improve sexual function that is sometimes diminished through the use of specific anabolic steroids.
When prolactin levels increase significantly, along with elevated levels of estrogen, this can induce gynecomastia (male breast enlargement). Even if estrogen is controlled, in ‘Gyno’ sensitive men heavily elevated levels of prolactin can still induce gynecomastia. The elevated levels of prolactin due to steroid use are most commonly associated with the Nandrolone (Deca Durabolin) and Trenbolone hormones. Not all men will have an issue with increases in prolactin due to the use of these steroids; it is somewhat dose dependent and highly dependent on genetic predispositions. However, if control is needed Pramipexole is a suitable option for control.
Benefits:
- Binds to dopamine receptors, increasing dopamine
- Decreases prolactin levels
- Raises growth hormone secretion levels
- Treatment for gynecomastia
- Treatment for erectile dysfunction
- Reduces refractory period
Terminal Half-life:
- 8-12 hrs
Possible Dosage & Cycle Length:
- Men @ 0.25-0.5 mg/twice per week, adjust as needed to mitigate side effects
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